It is also important to determine the methodology to be used for CT acquisition. For example, we position the patient with their arms down for head and neck malignancies but with their arms up for thoracic cancers. Detailed discussion of acquisition parameters is beyond the scope of this review but includes preparation of diabetic patients, strategies to minimise brown fat activation, as well as prescription of the extent of the field-of-view and the positioning of the patient to address the clinical question. Patient preparation is important in acquiring good quality studies and it is the responsibility of the PET specialist to ensure that appropriate protocols are in place to prevent non-diagnostic or suboptimal studies.
#Cine tracer alternative series#
Future articles in this series will address the use of other tracers pertinent to other cancers. In this article, we detail our approach to reviewing a PET/CT study using the most commonly used tracer, FDG.
#Cine tracer alternative how to#
Whilst there is a wealth of literature addressing the utility of PET in a large array of malignancies, the art of how to review and interpret PET/CT is generally acquired like an apprentice and not well addressed in the literature. This is a modality with many patterns of structural, physiologic and biochemical abnormalities that transcend the boundaries previously isolated in the worlds of nuclear medicine or radiology in characterising pathological conditions, particularly including cancer.
The process of reviewing PET/CT studies involves integration of the metabolic findings from the FDG component combined with the anatomical information provided by the CT component.
Integrating this “metabolic signature” into interpretation enables improved accuracy and characterisation of disease providing important prognostic information that may confer a high management impact and enable better personalised patient care.ġ8F-fluorodeoxyglucose (FDG) PET/CT imaging has become a key modality for imaging patients with cancer. Whilst FDG PET/CT performs well in the conventional imaging paradigm of identifying, counting and measuring tumour extent, a key paradigm change is its ability to non-invasively measure glycolytic metabolism. For interpretation, it is important to be aware of benign variants that demonstrate high glycolytic activity, and pathologic lesions which may not be FDG-avid, and understand the physiologic and biochemical basis of these findings. This encompasses how we display, threshold intensity of images and sequence our review, which are essential for accurate interpretation. In the manuscript we detail our approach to reviewing and reporting a PET/CT study using the most commonly used radiotracer, FDG. Interpretation requires integration of the metabolic and anatomic findings provided by the PET and CT components which transcend the knowledge base isolated in the worlds of nuclear medicine and radiology, respectively.
So I tried with both the Loft and Extrude effect and they both cause another strange effect as shown on the right hand object in the scene file below.18F-fluorodeoxyglucose (FDG) PET/CT is a pivotal imaging modality for cancer imaging, assisting diagnosis, staging of patients with newly diagnosed malignancy, restaging following therapy and surveillance. The next step I wanted to do was convert the heptagon spline to a polygon object. Thought you might like to know about the clipping if it may be caused by something else or is expected. However I do not see this glitch on the 7 sphere/1080 rotation version. To further explore and model the first scene you sent, I added an n-gon sweep to the 8 sphere/1234 rotation spline and it caused a strange clipping at the top point (see left object in scene file below “Clipped Top” in Object Manager). I haven’t looked at the tracer function yet as I’ve been looking at so many other areas, so good to see how this can be used. Thank you so much, it’s really opened my eyes to looking at things differently. I have just spent my lunch hour exploring the scene files.